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Newswise — Monthly eye injections of Avastin (bevacizumab) are as effective as the more expensive drug Eylea (aflibercept) for the treatment of central retinal vein occlusion (CRVO), according to a clinical trial funded by the National Eye Institute (NEI), part of the National Institutes of Health. “The bottom line is that in patients with CRVO-associated macular edema, Avastin was as effective as Eylea in terms of visual acuity after six months of treatment.”Retinal vein occlusion is the second most common retinal vascular disease after diabetic retinopathy and is estimated to affect more than 16 million adults worldwide.

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However, the lower proportion of eyes that had resolution of macular edema in the Avastin group did not translate into poorer visual acuity outcomes in that group at 6 months, said Scott.SCORE2 researchers will continue the study to investigate the cumulative effect of injections over a longer time frame and to evaluate the effects of residual edema.“There is little information about the long-term treatment needs of patients with CRVO-associated macular edema,” explained Scott.Become one of the individuals that have understood the privileges of online dating.Exchange messages with affectionate singles, view their photos, enter chat rooms for free, and date people that attract you.Additional funding was provided to the University of Wisconsin Department of Ophthalmology and Visual Sciences through an unrestricted grant from Research to Prevent Blindness.

Investigational drugs were provided by Regeneron and Allergan.Avastin is a less expensive anti-VEGF drug ( per dose, versus 50 per dose for Eylea).Avastin is an FDA approved biologic for treating cancer, but is frequently used off-label to treat conditions of the eye, including CRVO.SCORE2 results, published today in the Journal of the American Medical Association, show that average visual acuity in both groups improved about four lines on an eye chart, from about 20/100 visual acuity to 20/40 visual acuity.“This is a remarkable improvement in vision,” said Frederick Ferris, M.D., director of the Division of Epidemiology and Clinical Applications at NEI.NEI supports basic and clinical science programs to develop sight-saving treatments and address special needs of people with vision loss. About the National Institutes of Health (NIH): NIH, the nation’s medical research agency, includes 27 Institutes and Centers and is a component of the U. For more information about NIH and its programs, visit https://gov/.